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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIM37
All Species:
11.21
Human Site:
S490
Identified Species:
24.67
UniProt:
O94972
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94972
NP_001005207.1
964
107906
S490
E
G
G
P
T
T
A
S
V
R
E
A
K
E
D
Chimpanzee
Pan troglodytes
XP_511914
1136
126597
S662
E
G
G
P
T
T
A
S
V
R
E
A
K
E
D
Rhesus Macaque
Macaca mulatta
XP_001107200
963
107823
S490
E
G
G
P
T
T
A
S
I
R
E
A
K
E
D
Dog
Lupus familis
XP_853278
962
107845
A490
L
Q
D
G
S
T
T
A
S
V
R
E
V
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCX9
961
107641
A490
L
E
G
G
P
T
C
A
S
V
R
E
T
K
E
Rat
Rattus norvegicus
NP_001101758
1008
112512
A490
L
E
G
G
P
T
S
A
S
V
R
E
T
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509422
1125
125171
S503
L
E
S
G
P
A
T
S
G
R
E
S
K
E
E
Chicken
Gallus gallus
NP_001006224
983
108754
G490
L
E
S
V
A
A
P
G
L
V
R
D
N
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_695826
957
105706
K490
Q
A
A
S
V
E
T
K
E
D
E
D
E
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396821
1007
112716
R504
L
V
N
S
N
S
T
R
S
G
E
T
Y
Q
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791708
455
52591
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.5
98.8
94.8
N.A.
92.5
88.3
N.A.
71.7
79.7
N.A.
65.4
N.A.
N.A.
40.1
N.A.
36.9
Protein Similarity:
100
84.5
99.3
96.7
N.A.
95.1
91.1
N.A.
77
85.8
N.A.
74.4
N.A.
N.A.
56.4
N.A.
42.2
P-Site Identity:
100
100
93.3
6.6
N.A.
13.3
13.3
N.A.
33.3
0
N.A.
13.3
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
100
33.3
N.A.
33.3
40
N.A.
46.6
20
N.A.
26.6
N.A.
N.A.
26.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
10
19
28
28
0
0
0
28
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
10
0
19
0
0
28
% D
% Glu:
28
37
0
0
0
10
0
0
10
0
55
28
10
46
46
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
28
46
37
0
0
0
10
10
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
37
37
10
% K
% Leu:
55
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
10
0
0
0
0
0
0
0
10
0
10
% N
% Pro:
0
0
0
28
28
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
10
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
37
37
0
0
0
0
% R
% Ser:
0
0
19
19
10
10
10
37
37
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
28
55
37
0
0
0
0
10
19
0
0
% T
% Val:
0
10
0
10
10
0
0
0
19
37
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _